LabsTrail is an open registry that rates the quality of life-science papers, recording each paper and each of its ratings off-chain on the OriginTrail DKG and on-chain on Base.
Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro's clinical journey
ipfs://bafybeia54htwu…sp5sfhgiRead (in progress)
Title, authors and abstract taken from the PDF
Saved off-chain
The record is written to OriginTrail's knowledge graph
Minted on-chain
The asset is minted on Base by OriginTrail's Knowledge Asset contracts, with its merkle root
Published
Anyone can check who submitted it
The newest records on the knowledge graph. Open one to check who submitted it.
Many published results can't be repeated, yet trust in a paper still comes mostly from the journal it appeared in, and the reviews behind that trust are rarely public. AI agents now read and build on papers at a scale no person can, with no better way to tell which ones give enough to be repeated.
LabsTrail records each paper, with who submitted it and which exact file, then rates its quality in the open: a machine reproducibility score first, transparent human review next. The paper and each rating are recorded off-chain and on-chain.
Why LabsTrail, in more detailLabsTrail publishes each paper on the OriginTrail Decentralized Knowledge Graph (DKG) as a Knowledge Asset: a set of linked statements about the paper, with an owner and a proof on-chain. Its content and its proof live in two places that check each other.
DKG nodes store the asset's statements: title, authors, the PDF's link, the submitter, their signature and its deadline. Once published, OriginTrail replicates them across the context graph's nodes, and any node subscribed to LabsTrail's graph can fetch them by the UAL, the asset's permanent address.
Publishing mints the asset on Base as an ERC-721 token and anchors the merkle root of its statements, one hash computed from all of them. Any node can check that the content still matches that root. Only the token's holder can update the asset, and each update anchors a new root under the same UAL.
Three steps and one signature. No gas.
Your address becomes the submitter on the record.
It's stored on IPFS. We read its title, authors and abstract, and check it's a life-science or health paper.
Signing is free and sends no transaction. We mint the record and pay its fees.
Anyone with a wallet can ask for a rating of a published paper, from its page. Each phase adds its own score on-chain, and earlier scores stay as they were.
Pick a paper to rateAn AI model checks the whole paper against the checklists for the kinds of study it reports: does it give what others need to reproduce the work? The score, from 0 to 100, goes on-chain. It doesn't say whether the results hold.
Reviewers drawn at random with Chainlink VRF, so anyone can check the draw was fair, read the paper and score it. Their score is recorded next to the first one.
A lab repeats the experiments, then reviewers check its results. That verdict is recorded as a third score, next to the first two.
The statements DKG nodes store for each paper: its details, a permanent link to the PDF, and your signature. The merkle root on Base covers all of them, so anyone can check who submitted it without trusting us.
A rating is a separate asset, with its own UAL, whose statements point to this one. The paper asset itself never changes.
| Paper |
|---|
The interplay of epigenetic remodelling and transposon-mediated genomic instability in ageing and longevity Aaron J J Lemus, Eyael Tewelde, Rajyk Bhala +3 more 77phase 10x9a17…9111Valid |
Boundary issues: SWI/SNF shapes chromatin patterns in and around centromeres Karen A Lane, Alison Harrod, Jessica Downs 71phase 10x9a17…9111Valid |
-Cyclin B mediated phosphorylation of PP2A-B56 on B56 Par1 .T73T75 controls mitotic entry timing and Schizosaccharomyces pombe cell size Lenka Halova, Yvonne Connolly, Duncan Smith +2 more 80phase 10x9a17…9111Valid |
Contribution of mechanical forces in multiciliated cell differentiation Nathalie Delgehyr, Nathalie Spassky 91phase 10x9a17…9111Valid |
Emerging role for R-loops in chromosome segregation Munira A Basrai, Prashant K Mishra 82phase 10x9a17…9111Valid |